An Examination of the Treponemal Wassermann Reaction and Reiter Protein Complement-Fixation Test

An examination of the treponemal Wassermann reaction and Reiter protein complement-fixation test.

Less than one year after the description of the Treponema pallidum by Schaudinn and Hoffman, the first report of the application of the complementfixation reaction of Bordet and Gengou (1901) to the diagnosis of human syphilis was published in Budapest by Detre (1906), exactly 2 weeks after the appearance of the classical paper "A Sero-diagnostic Reaction in Syphilis" by Wassermann, Neisser, an...

An Examination of the Treponemal Wassermann Reaction and Reiter Protein Complement-fixation

Less than one year after the description of the Treponema pallidum by Schaudinn and Hoffman, the first report of the application of the complementfixation reaction of Bordet and Gengou (1901) to the diagnosis of human syphilis was published in Budapest by Detre (1906), exactly 2 weeks after the appearance of the classical paper "A Sero-diagnostic Reaction in Syphilis" by Wassermann, Neisser, an...

Results of parallel tests with the Reiter protein complement-fixation test, the treponemal immobilization test. and the treponemal Wassermann reaction on 1,046 sera.

The Treponemal Immobilization Test (TPI) is now generally accepted as a highly sensitive and specific test for treponemal infection, but its complexity and the difficulties inherent in the use of a living organism as antigen have restricted its performance to specialized laboratories. These limitations have led to the re-investigation of the cultivable strains of treponemes as antigens for the ...

The Reiter protein complement-fixation test using the Auto-Analyzer.

A method for the Reiter protein complement-fixation test using the Techncon AutoAnalyzer is described. Two hundred and fifty sera were tested, when six false-positive and nine false-negative results were obtained when compared with results obtained by the manual method. Deep freezing the sera before testing on the AutoAnalyzer increased the sensitivity so that in a further 250 sera tested no fa...

Automatic apparatus for Wassermann and Reiter complement-fixation tests utilizing the 'discrete-analysis' principle.